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It prevents progression of anemia and nerve damage by supplying B directly, even when intrinsic factor (the gastric protein needed for oral B12 absorption) is lacking

Previous studies have reported inconsistent results when comparing oral, sublingual, and intramuscular administration, often limited by small sample sizes or heterogeneous populations (Vidal-Alaball et al., 2006

Unlike many existing drugs that primarily target appetite suppression, Tesofensine is believed to influence multiple pathways within the brain, potentially impacting both appetite and energy expenditure

PMC 11448733

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